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Pregnant women infected with HIV are more liekly to spread the virus to their children if they are carrying twins,according to a report in the journal AIDS.Laurent Mandelbrot of the University of Paris,and associates investigated mother-to-child spread of HIV in twins,compared with single twins,compared with single infants,born to HIV-infected mothers in the French Perinatal HIV Cohort.Before the advent of highly active antiretroviral therapy,an effective combination of anti-HIV drugs,the mother-to-child HIV transmission rate in twin pregnancies was two to three times that in singleton pregnancies.